Let me guess: you were trying to pirate Windows games and software. Right?

If yes, look at it this way. You’re pirating games for one system, and trying to run them in another system. Of course it’ll involve one or two additional loops to make it work. It’s like baking bread on your stove, you know? It can be done, but it isn’t as streamlined as using your oven.

That said it isn’t really difficult. I have a bunch of pirated Windows games installed in my Linux. Steam helps by a lot, because of Proton; add the game to Steam as a “non-Steam game”, then force it to use a specific Steam Play compatibility tool. You can do it without Steam but it streamlines everything.

You’re still better off looking for native software, though, made for Linux. A bunch of good games have Linux versions.