Sometimes it can. Google and Samsung never had an issue though. The more ad lists you setup the more false-positives you get.
But 99% of the time it’s fine. The other 1% you open the dashboard and look at the last few blocks and whitelist whatever it causing issues.
BTRBK for easy BTRFS snapshots to an external drive.
Rsync to also upload those to B2 compatible storage (encrypted)