

It should work. The only practical issues are:
- Usually, you will have to manually install the proprietary drivers (I think Fedora makes this relatively easy)
- Wayland (the protocol most desktop environmentss use nowadays) support may be hit-and-miss at times (it will mostly work but it’s not as polished as with Intel/AMD), and Proton (the thing that lets you play Windows games) may not play well either.
The ideological issue (which you probably don’t care about) is that it pretty much requires proprietary (non-FOSS) drivers which run in kernel space and so in theory have complete access to all data on your computer (but then so does Intel ME). This is the main reason I personally will never use NVidia cards.
How is nouveau doing for those older cards these days? Are they at least still usable as a display adapter?